› 6uyz

X-ray diffraction
1.4Å resolution

Crystal structure of K46-acetylated SUMO1 in complex with phosphorylated DAXX

Released:
DOI: 10.2210/pdb6uyz/pdb
PDB entry 6uyz coloured by chain, front view.
PDB entry 6uyz coloured by chain, side view.
PDB entry 6uyz coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Mascle XH, Gagnon C, Wahba HM, Lussier-Price M, Cappadocia L, Sakaguchi K, Omichinski JG
Structure 28 157-168.e5 (2020)
PMID: 31879127

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159012 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Small ubiquitin-related modifier 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 83 amino acids
Theoretical weight: 9.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P63165 (Residues: 17-97; Coverage: 80%)
Gene names: OK/SW-cl.43, SMT3C, SMT3H3, SUMO1, UBL1
Sequence domains: Ubiquitin-2 like Rad60 SUMO-like
phosphorylated DAXX Chains: B, D
Molecule details ›
Chains: B, D
Length: 17 amino acids
Theoretical weight: 2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
2 modified residues:
Ligand ALY 2 x ALY
Ligand SEP 4 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 100.224Å b: 38.316Å c: 67.721Å
α: 90° β: 119.91° γ: 90°
R-values:
R R work R free
0.16 0.159 0.181
Expression system: Escherichia coli

Quick links

Citations

3 review citations

PML nuclear bodies and chromatin dynamics: catch me if you can!
Corpet et al. (2020)
2 more