6up7

Electron Microscopy
4.2Å resolution

neurotensin receptor and arrestin2 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-151862 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Neurotensin Chain: C
Molecule details ›
Chain: C
Length: 6 amino acids
Theoretical weight: 819 Da
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P30990 (Residues: 158-163; Coverage: 4%)
Gene name: NTS
Beta-arrestin-1 Chain: B
Molecule details ›
Chain: B
Length: 348 amino acids
Theoretical weight: 39.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P49407 (Residues: 8-355; Coverage: 83%)
Gene names: ARR1, ARRB1
Sequence domains:
Neurotensin receptor type 1 Chain: R
Molecule details ›
Chain: R
Length: 334 amino acids
Theoretical weight: 37.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P30989 (Residues: 50-383; Coverage: 80%)
Gene names: NTRR, NTSR1
Sequence domains: 7 transmembrane receptor (rhodopsin family)
unidentified peptide Chain: V
Molecule details ›
Chain: V
Length: 9 amino acids
Theoretical weight: 784 Da
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-20836
Expression system: Spodoptera frugiperda