› 6u9q

X-ray diffraction
1.83Å resolution

Crystal Structure Analysis of DNA-BCL11A Znf domain complex

Released:
DOI: 10.2210/pdb6u9q/pdb
PDB entry 6u9q coloured by chain, front view.
PDB entry 6u9q coloured by chain, side view.
PDB entry 6u9q coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Seo H-S, Dhe-Paganon S

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120685 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
B-cell lymphoma/leukemia 11A Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H165 (Residues: 730-835; Coverage: 13%)
Gene names: BCL11A, CTIP1, EVI9, KIAA1809, ZNF856
Sequence domains: Zinc finger, C2H2 type
DNA5 Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 3.99 KDa
Source organism: Homo sapiens
Expression system: Not provided
DNA3 Chain: C
Molecule details ›
Chain: C
Length: 13 nucleotides
Theoretical weight: 3.95 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand ZN 3 x ZN
Ligand PO4 2 x PO4
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 101Å b: 60.16Å c: 75.79Å
α: 90° β: 129.73° γ: 90°
R-values:
R R work R free
0.176 0.175 0.195
Expression systems:
  • Escherichia coli
  • Not provided

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