6twx

X-ray diffraction
2.3Å resolution

MAGI1_2 complexed with a phosphorylated 16E6 peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-136586 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Annexin A2; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 427 amino acids
Theoretical weight: 48.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96QZ7 (Residues: 455-558; Coverage: 7%)
  • Canonical: P07355 (Residues: 22-339; Coverage: 94%)
Gene names: AIP3, ANX2, ANX2L4, ANXA2, BAIAP1, BAP1, CAL1H, LPC2D, MAGI1, TNRC19
Sequence domains:
Protein E6 Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 amino acids
Theoretical weight: 1.32 KDa
Source organism: Human papillomavirus 16
Expression system: Not provided
UniProt:
  • Canonical: P03126 (Residues: 149-158; Coverage: 6%)
Gene name: E6

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Unit cell:
a: 61.47Å b: 96.55Å c: 198.52Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.209 0.259
Expression systems:
  • Escherichia coli
  • Not provided