› 6tl7

X-ray diffraction
1.11Å resolution

CRYSTAL STRUCTURE OF LECTIN-LIKE OX-LDL RECEPTOR 1 (P212121)

Released:
DOI: 10.2210/pdb6tl7/pdb
PDB entry 6tl7 coloured by chain, front view.
PDB entry 6tl7 coloured by chain, side view.
PDB entry 6tl7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state
Nar H, Fiegen D, Schnapp G
Commun Chem (2020)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxidized low-density lipoprotein receptor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 135 amino acids
Theoretical weight: 15.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P78380 (Residues: 143-273; Coverage: 48%)
Gene names: CLEC8A, LOX1, OLR1
Sequence domains: Lectin C-type domain

Ligands and Environments

1 bound ligand:
Ligand NI 2 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 40.49Å b: 64.7Å c: 101.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.132 0.132 0.162
Expression system: Escherichia coli

Quick links