6szv

Electron Microscopy
2.5Å resolution

Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-124820 (preferred)
Entry contents:
3 distinct polypeptide molecules
3 distinct RNA molecules
Macromolecules (6 distinct):
Polymerase acidic protein Chain: A
Molecule details ›
Chain: A
Length: 738 amino acids
Theoretical weight: 85.49 KDa
Source organism: Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: H6QM92 (Residues: 1-713; Coverage: 100%)
Gene name: PA
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PA
RNA-directed RNA polymerase catalytic subunit Chain: B
Molecule details ›
Chain: B
Length: 776 amino acids
Theoretical weight: 87.94 KDa
Source organism: Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: H6QM91 (Residues: 1-756; Coverage: 100%)
Gene name: PB1
Sequence domains: Influenza RNA-dependent RNA polymerase subunit PB1
5' vRNA Chain: V
Molecule details ›
Chain: V
Length: 14 nucleotides
Theoretical weight: 4.56 KDa
3' vRNA Chain: R
Molecule details ›
Chain: R
Length: 21 nucleotides
Theoretical weight: 6.53 KDa
Capped mRNA Chain: M
Molecule details ›
Chain: M
Length: 26 nucleotides
Theoretical weight: 8.92 KDa

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.5Å
Relevant EMDB volumes: EMD-10355
Expression system: Trichoplusia ni