› 6snv

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153773 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA mismatch repair protein MLH1 Chains: A, D
Molecule details ›
Chains: A, D
Length: 265 amino acids
Theoretical weight: 30.76 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P38920 (Residues: 505-769; Coverage: 35%)
Gene names: MLH1, PMS2, YM8520.16, YMR167W
Sequence domains: DNA mismatch repair protein Mlh1 C-terminus
DNA mismatch repair protein MLH3 Chains: B, E
Molecule details ›
Chains: B, E
Length: 239 amino acids
Theoretical weight: 27.77 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12083 (Residues: 477-715; Coverage: 33%)
Gene names: MLH3, P2550, YPL164C

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21212
Unit cell:
a: 90.893Å b: 134.806Å c: 102.569Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.229 0.271
Expression system: Escherichia coli

Quick links

Citations

9 citation in other articles

Cilia regulate meiotic recombination in zebrafish.
Xie et al. (2022)
8 more