› 6s13

Electron Microscopy
3.58Å resolution

Erythromycin Resistant Staphylococcus aureus 70S ribosome (delta R88 A89 uL22).

Released:
DOI: 10.2210/pdb6s13/pdb
PDB entry 6s13 coloured by chain, front view.
PDB entry 6s13 coloured by chain, side view.
PDB entry 6s13 coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Halfon Y, Matzov D, Eyal Z, Bashan A, Zimmerman E, Kjeldgaard J, Ingmer H, Yonath A
Sci Rep 9 11460 (2019)
PMID: 31391518
Related structures: EMD-10079

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 52-mer (preferred)
PDBe Complex ID:
PDB-CPX-236593 (preferred)
Entry contents:
49 distinct polypeptide molecules
3 distinct RNA molecules
Macromolecules (52 distinct):
Large ribosomal subunit protein uL2 Chain: C
Molecule details ›
Chain: C
Length: 274 amino acids
Theoretical weight: 29.83 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: B3VKN3 (Residues: 2-275; Coverage: 99%)
Gene names: rap, rplB
Sequence domains:
Large ribosomal subunit protein uL3 Chain: D
Molecule details ›
Chain: D
Length: 215 amino acids
Theoretical weight: 23.2 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8U3W0 (Residues: 2-216; Coverage: 98%)
Gene names: CD116_01800, ERS140147_00638, NCTC13712_02198, rplC
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 Chain: E
Molecule details ›
Chain: E
Length: 206 amino acids
Theoretical weight: 22.36 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TRC7 (Residues: 2-207; Coverage: 100%)
Gene names: A6760_13475, BN1321_380081, CV021_17920, E1948_03020, E1948_11875, EP54_02080, EQ90_01285, FAF17_03860, G6W63_05865, G6Y24_08895, GO793_01620, GO814_07405, GO941_08955, GO942_01145, GQX37_14780, GZ156_01175, GZ163_04695, H2639_07665, HMPREF3211_01574, M1K003_0792, NCTC10702_03547, NCTC13131_01592, NCTC6133_03039, NCTC7972_02461, QU38_05015, SAMEA2078260_00068, SAMEA2078588_00375, SAMEA2080344_00552, SAMEA2081063_01545, SAMEA4008575_01032, SAMEA70146418_00484, SAMEA70153168_01235, SAMEA70245418_00536, rplD, rplD_1
Sequence domains: Ribosomal protein L4/L1 family
Large ribosomal subunit protein uL5 Chain: F
Molecule details ›
Chain: F
Length: 175 amino acids
Theoretical weight: 19.73 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TUC3 (Residues: 2-176; Coverage: 98%)
Gene names: A6760_13420, BN1321_380070, E1948_03075, E1948_11820, EP54_02135, EQ90_01230, FAF17_03805, G6W63_05920, G6Y24_08840, GO793_01675, GO814_07350, GO941_09010, GO942_01090, GQX37_14835, GZ156_01230, GZ163_04640, H2639_07610, M1K003_0781, NCTC13131_01581, NCTC5664_01674, NCTC7878_01021, NCTC7972_02472, QU38_04960, SAMEA1531744_00350, SAMEA2078260_00057, SAMEA2078588_00364, SAMEA2080344_00563, SAMEA2081063_01556, SAMEA4008575_01043, SAMEA70146418_00495, SAMEA70153168_01224, SAMEA70245418_00547, rplE, rplE_1
Sequence domains:
Large ribosomal subunit protein uL6 Chain: G
Molecule details ›
Chain: G
Length: 175 amino acids
Theoretical weight: 19.5 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8U3X2 (Residues: 2-176; Coverage: 98%)
Gene names: A6760_13405, CV021_17990, E1948_03090, E1948_11805, EP54_02150, EQ90_01215, FAF17_03790, G6W63_05935, G6Y24_08825, GO814_07335, GO941_09025, GO942_01075, GQX37_14850, GZ156_01245, GZ163_04625, H2639_07595, HMPREF3211_01560, M1K003_0778, NCTC13131_01578, NCTC5664_01677, NCTC6133_03025, NCTC7972_02475, QU38_04945, SAMEA1531744_00347, SAMEA2078260_00054, SAMEA2078588_00361, SAMEA2080344_00566, SAMEA2081063_01559, SAMEA4008575_01046, SAMEA70146418_00498, SAMEA70153168_01221, SAMEA70245418_00550, rplF, rplF_1
Sequence domains: Ribosomal protein L6
Large ribosomal subunit protein uL13 Chain: H
Molecule details ›
Chain: H
Length: 145 amino acids
Theoretical weight: 16.36 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TUE6 (Residues: 1-145; Coverage: 100%)
Gene names: CD116_01960, ERS140147_00605, NCTC13712_02165, rplM
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL14 Chain: I
Molecule details ›
Chain: I
Length: 122 amino acids
Theoretical weight: 13.16 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UUA0 (Residues: 1-122; Coverage: 100%)
Gene names: CD116_01850, ERS140147_00628, NCTC13712_02188, rplN
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein uL15 Chain: J
Molecule details ›
Chain: J
Length: 146 amino acids
Theoretical weight: 15.63 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UGA7 (Residues: 1-146; Coverage: 100%)
Gene names: CD116_01895, ERS140147_00619, NCTC13712_02179, rplO
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Large ribosomal subunit protein uL16 Chain: K
Molecule details ›
Chain: K
Length: 137 amino acids
Theoretical weight: 15.6 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077V4G0 (Residues: 1-137; Coverage: 95%)
Gene names: CD116_01835, ERS140147_00631, NCTC13712_02191, rplP
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein bL17 Chain: L
Molecule details ›
Chain: L
Length: 120 amino acids
Theoretical weight: 13.58 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UG91 (Residues: 3-122; Coverage: 98%)
Gene names: CD116_01935, ERS140147_00611, NCTC13712_02171, rplQ
Sequence domains: Ribosomal protein L17
Large ribosomal subunit protein uL18 Chain: M
Molecule details ›
Chain: M
Length: 119 amino acids
Theoretical weight: 13.12 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TRE0 (Residues: 1-119; Coverage: 100%)
Gene names: A6760_13400, BN1321_380066, CV021_17995, E1948_03095, E1948_11800, EP54_02155, EQ90_01210, FAF17_03785, G6W63_05940, G6Y24_08820, GO793_01695, GO814_07330, GO941_09030, GO942_01070, GQX37_14855, GZ156_01250, GZ163_04620, H2639_07590, HMPREF3211_01559, M1K003_0777, NCTC13131_01577, NCTC5664_01678, NCTC6133_03024, NCTC7972_02476, QU38_04940, SAMEA1531744_00346, SAMEA2078260_00053, SAMEA2078588_00360, SAMEA2080344_00567, SAMEA2081063_01560, SAMEA4008575_01047, SAMEA70146418_00499, SAMEA70153168_01220, SAMEA70245418_00551, rplR, rplR_1
Sequence domains: Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
Large ribosomal subunit protein bL19 Chain: N
Molecule details ›
Chain: N
Length: 114 amino acids
Theoretical weight: 13.1 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UVB6 (Residues: 2-115; Coverage: 98%)
Gene names: CD116_13000, ERS140147_00145, NCTC13712_01186, rplS
Sequence domains: Ribosomal protein L19
Large ribosomal subunit protein bL20 Chain: O
Molecule details ›
Chain: O
Length: 116 amino acids
Theoretical weight: 13.46 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077VMP6 (Residues: 2-117; Coverage: 98%)
Gene names: CD116_08935, ERS140147_00901, NCTC13712_01667, rplT
Sequence domains: Ribosomal protein L20
Large ribosomal subunit protein bL21 Chain: P
Molecule details ›
Chain: P
Length: 102 amino acids
Theoretical weight: 11.35 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: D7URR3 (Residues: 1-102; Coverage: 100%)
Gene names: A6760_00855, BN1321_260285, CV021_08845, E1948_03740, E1948_08440, EP54_09325, EQ90_02350, G6W63_07760, G6Y24_01405, GO793_02930, GO793_12510, GO814_13145, GO941_09800, GO942_04920, GZ156_05380, GZ163_10025, H2639_01150, HMPREF3211_01799, M1K003_1398, NCTC10702_02586, NCTC5664_03625, NCTC6133_02189, NCTC7878_03166, NCTC7972_00279, QU38_08695, SAMEA1531744_00125, SAMEA70153168_00214, SAMEA70245418_00778, rplU
Sequence domains: Ribosomal prokaryotic L21 protein
Large ribosomal subunit protein uL22 Chain: Q
Molecule details ›
Chain: Q
Length: 110 amino acids
Theoretical weight: 12.1 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UKF9 (Residues: 1-112; Coverage: 94%)
Gene names: CD116_01825, ERS140147_00633, NCTC13712_02193, rplV
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein uL23 Chain: R
Molecule details ›
Chain: R
Length: 89 amino acids
Theoretical weight: 10.38 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TUB4 (Residues: 2-90; Coverage: 98%)
Gene names: A6760_13470, BN1321_380080, CV021_17925, E1948_03025, E1948_11870, EP54_02085, EQ90_01280, FAF17_03855, G6W63_05870, G6Y24_08890, GO793_01625, GO814_07400, GO941_08960, GO942_01140, GQX37_14785, GZ156_01180, GZ163_04690, H2639_07660, HMPREF3211_01573, M1K003_0791, NCTC10702_03546, NCTC13131_01591, NCTC6133_03038, NCTC7878_01010, NCTC7972_02462, QU38_05010, SAMEA1531744_00360, SAMEA2078260_00067, SAMEA2078588_00374, SAMEA2080344_00553, SAMEA2081063_01546, SAMEA4008575_01033, SAMEA70146418_00485, SAMEA70153168_01234, SAMEA70245418_00537, rplW, rplW_1
Sequence domains: Ribosomal protein L23
Large ribosomal subunit protein uL24 Chain: S
Molecule details ›
Chain: S
Length: 103 amino acids
Theoretical weight: 11.32 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TRD5 (Residues: 2-104; Coverage: 98%)
Gene names: A6760_13425, BN1321_380071, CV021_17970, E1948_03070, E1948_11825, EP54_02130, EQ90_01235, FAF17_03810, G6W63_05915, G6Y24_08845, GO793_01670, GO814_07355, GO941_09005, GO942_01095, GQX37_14830, GZ156_01225, GZ163_04645, H2639_07615, HMPREF3211_01564, M1K003_0782, NCTC10702_03537, NCTC13131_01582, NCTC5664_01673, NCTC6133_03029, NCTC7878_01020, NCTC7972_02471, QU38_04965, SAMEA1531744_00351, SAMEA2078260_00058, SAMEA2078588_00365, SAMEA2080344_00562, SAMEA2081063_01555, SAMEA4008575_01042, SAMEA70146418_00494, SAMEA70153168_01225, SAMEA70245418_00546, rplX, rplX_1
Sequence domains:
Large ribosomal subunit protein bL25 Chain: T
Molecule details ›
Chain: T
Length: 94 amino acids
Theoretical weight: 10.46 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A133Q8Z9 (Residues: 4-97; Coverage: 43%)
Gene names: HMPREF3211_00359, ctc, rplY
Sequence domains: Ribosomal L25p family
Large ribosomal subunit protein bL27 Chain: U
Molecule details ›
Chain: U
Length: 82 amino acids
Theoretical weight: 8.91 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077ULC5 (Residues: 12-93; Coverage: 87%)
Gene names: CD116_08800, ERS140147_00927, NCTC13712_01641, rpmA
Sequence domains: Ribosomal L27 protein
Large ribosomal subunit protein bL28 Chain: V
Molecule details ›
Chain: V
Length: 58 amino acids
Theoretical weight: 6.55 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077URJ8 (Residues: 3-60; Coverage: 94%)
Gene names: CD116_12910, ERS140147_00162, NCTC13712_01169, rpmB
Sequence domains: Ribosomal L28 family
Large ribosomal subunit protein uL29 Chain: W
Molecule details ›
Chain: W
Length: 67 amino acids
Theoretical weight: 7.85 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077W1J5 (Residues: 2-68; Coverage: 97%)
Gene names: CD116_01840, ERS140147_00630, NCTC13712_02190, rpmC
Sequence domains: Ribosomal L29 protein
Large ribosomal subunit protein uL30 Chain: X
Molecule details ›
Chain: X
Length: 58 amino acids
Theoretical weight: 6.43 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8UVN7 (Residues: 2-59; Coverage: 98%)
Gene names: A6760_13390, BN1321_380064, CV021_18005, E1948_03105, E1948_11790, EP54_02165, EQ90_01200, FAF17_03775, G6W63_05950, G6Y24_08810, GO793_01705, GO814_07320, GO941_09040, GO942_01060, GQX37_14865, GZ156_01260, GZ163_04610, H2639_07580, HMPREF3211_01557, M1K003_0775, NCTC10702_03528, NCTC13131_01575, NCTC5664_01681, NCTC6133_03022, NCTC7878_01028, NCTC7972_02478, QU38_04930, SAMEA1531744_00344, SAMEA2078260_00051, SAMEA2078588_00358, SAMEA2080344_00569, SAMEA2081063_01562, SAMEA4008575_01049, SAMEA70146418_00501, SAMEA70153168_01218, SAMEA70245418_00553, rpmD, rpmD_1
Sequence domains: Ribosomal protein L30p/L7e
Large ribosomal subunit protein bL31B Chain: Y
Molecule details ›
Chain: Y
Length: 59 amino acids
Theoretical weight: 6.91 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A380EL30 (Residues: 1-59; Coverage: 47%)
Gene names: NCTC10702_03348, rpmE2
Sequence domains: Ribosomal protein L31
50S ribosomal protein L32 Chain: Z
Molecule details ›
Chain: Z
Length: 48 amino acids
Theoretical weight: 5.57 KDa
Source organism: Staphylococcus aureus
Large ribosomal subunit protein bL33 Chain: 1
Molecule details ›
Chain: 1
Length: 47 amino acids
Theoretical weight: 5.68 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077V2P0 (Residues: 2-48; Coverage: 96%)
Gene names: CD116_07290, ERS140147_01724, NCTC13712_01328, rpmG, rpmG2, rpmG2_1
Sequence domains: Ribosomal protein L33
Large ribosomal subunit protein bL34 Chain: 2
Molecule details ›
Chain: 2
Length: 43 amino acids
Theoretical weight: 5.25 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TQ59 (Residues: 2-44; Coverage: 96%)
Gene names: CD116_00205, ERS140147_01157, NCTC13712_02668, rpmH
Sequence domains: Ribosomal protein L34
Large ribosomal subunit protein bL35 Chain: 3
Molecule details ›
Chain: 3
Length: 64 amino acids
Theoretical weight: 7.46 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UL47 (Residues: 2-65; Coverage: 97%)
Gene names: CD116_08940, ERS140147_00900, NCTC13712_01668, rpmI
Sequence domains: Ribosomal protein L35
Large ribosomal subunit protein bL36 Chain: 4
Molecule details ›
Chain: 4
Length: 37 amino acids
Theoretical weight: 4.32 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UGV8 (Residues: 1-37; Coverage: 100%)
Gene names: CD116_01915, ERS140147_00615, NCTC13712_02175, rpmJ
Sequence domains: Ribosomal protein L36
Small ribosomal subunit protein uS2 Chain: b
Molecule details ›
Chain: b
Length: 226 amino acids
Theoretical weight: 25.93 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A2X2M020 (Residues: 1-226; Coverage: 97%)
Gene names: NCTC7878_01855, rpsB
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein uS3 Chain: c
Molecule details ›
Chain: c
Length: 202 amino acids
Theoretical weight: 22.68 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UU26 (Residues: 2-203; Coverage: 93%)
Gene names: CD116_01830, ERS140147_00632, NCTC13712_02192, rpsC
Sequence domains:
Small ribosomal subunit protein uS4 Chain: d
Molecule details ›
Chain: d
Length: 198 amino acids
Theoretical weight: 22.85 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TVK2 (Residues: 3-200; Coverage: 99%)
Gene names: BN1321_260351, CV021_05220, E1948_04080, E1948_08795, EP54_00845, EQ90_06385, FAF17_15630, G6W63_12880, G6Y24_12375, GO814_13650, GO942_04570, GQX37_04495, GZ156_10760, GZ163_10960, H2639_00770, HMPREF3211_02281, M1K003_2482, NCTC10702_02696, NCTC13131_06120, NCTC5664_03740, NCTC6133_02294, NCTC7972_00210, QU38_08340, SAMEA1531744_00061, SAMEA2078260_02121, SAMEA2078588_01950, SAMEA2080344_02017, SAMEA2081063_02008, SAMEA4008575_02112, SAMEA70146418_02346, SAMEA70153168_00150, SAMEA70245418_00710, rpsD, rpsD_2
Sequence domains:
Small ribosomal subunit protein uS5 Chain: e
Molecule details ›
Chain: e
Length: 156 amino acids
Theoretical weight: 16.52 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TUC9 (Residues: 10-165; Coverage: 94%)
Gene names: A6760_13395, BN1321_380065, CV021_18000, E1948_03100, E1948_11795, EP54_02160, EQ90_01205, FAF17_03780, G6W63_05945, G6Y24_08815, GO793_01700, GO814_07325, GO941_09035, GO942_01065, GQX37_14860, GZ156_01255, GZ163_04615, H2639_07585, HMPREF3211_01558, M1K003_0776, NCTC13131_01576, NCTC6133_03023, NCTC7878_01027, NCTC7972_02477, QU38_04935, SAMEA1531744_00345, SAMEA2078260_00052, SAMEA2078588_00359, SAMEA2080344_00568, SAMEA2081063_01561, SAMEA4008575_01048, SAMEA70146418_00500, SAMEA70153168_01219, SAMEA70245418_00552, rpsE, rpsE_1
Sequence domains:
Small ribosomal subunit protein bS6 Chain: f
Molecule details ›
Chain: f
Length: 95 amino acids
Theoretical weight: 11.24 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8TPC6 (Residues: 1-95; Coverage: 97%)
Gene names: CD116_05330, ERS140147_02571, NCTC13712_00312, rpsF
Sequence domains: Ribosomal protein S6
Small ribosomal subunit protein uS7 Chain: g
Molecule details ›
Chain: g
Length: 152 amino acids
Theoretical weight: 17.18 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077VHU6 (Residues: 1-152; Coverage: 97%)
Gene names: CD116_12315, ERS140147_01024, NCTC13712_00499, rpsG
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein uS8 Chain: h
Molecule details ›
Chain: h
Length: 131 amino acids
Theoretical weight: 14.72 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8U8T8 (Residues: 2-132; Coverage: 99%)
Gene names: CD116_01870, ERS140147_00624, NCTC13712_02184, rpsH
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein uS9 Chain: i
Molecule details ›
Chain: i
Length: 127 amino acids
Theoretical weight: 14.31 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A1Q4GY48 (Residues: 4-130; Coverage: 98%)
Gene names: A6760_13315, E1948_03180, EP54_02240, EQ90_01125, QU38_03565, rpsI
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein uS10 Chain: j
Molecule details ›
Chain: j
Length: 97 amino acids
Theoretical weight: 11.01 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A0H2K0A0 (Residues: 6-102; Coverage: 95%)
Gene names: CD116_01795, ERS140147_00639, NCTC13712_02199, rpsJ
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein uS11 Chain: k
Molecule details ›
Chain: k
Length: 114 amino acids
Theoretical weight: 12.05 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UKD6 (Residues: 15-128; Coverage: 88%)
Gene names: CD116_01925, ERS140147_00613, NCTC13712_02173, rpsK
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS12 Chain: l
Molecule details ›
Chain: l
Length: 135 amino acids
Theoretical weight: 15.08 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A133PZQ5 (Residues: 14-148; Coverage: 91%)
Gene names: HMPREF3211_01391, rpsL
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein uS13 Chain: m
Molecule details ›
Chain: m
Length: 104 amino acids
Theoretical weight: 11.99 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8U8U6 (Residues: 7-110; Coverage: 86%)
Gene names: A6760_13360, BN1321_380059, CV021_18035, E1948_03135, E1948_11760, EP54_02195, EQ90_01170, FAF17_03745, G6W63_05980, G6Y24_08780, GO793_04170, GO814_07290, GO941_10770, GO942_01030, GQX37_14895, GZ156_01290, GZ163_04580, H2639_07550, HMPREF3211_01551, M1K003_0769, NCTC13131_01569, NCTC5664_01688, NCTC6133_03016, NCTC7878_01035, NCTC7972_02484, QU38_04900, SAMEA1531744_00338, SAMEA2078260_00045, SAMEA2078588_00352, SAMEA2080344_00575, SAMEA2081063_01568, SAMEA4008575_01055, SAMEA70146418_00507, SAMEA70153168_01212, SAMEA70245418_00559, rpsM, rpsM_1
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein uS14 Chain: n
Molecule details ›
Chain: n
Length: 60 amino acids
Theoretical weight: 7.19 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UGW7 (Residues: 2-61; Coverage: 98%)
Gene names: CD116_01865, ERS140147_00625, NCTC13712_02185, rpsN, rpsN1, rpsN_1, rpsZ
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein uS15 Chain: o
Molecule details ›
Chain: o
Length: 88 amino acids
Theoretical weight: 10.5 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8U6H8 (Residues: 2-89; Coverage: 99%)
Gene names: A6760_04710, BN1321_240121, CV021_03145, E1948_05660, E1948_06230, EP54_08785, EQ90_07875, FAF17_12360, G6W63_11835, G6Y24_07945, GO793_17005, GO814_06080, GO941_10135, GO942_07530, GQX37_06725, GZ156_08325, GZ163_05945, H2639_04650, HMPREF3211_01317, M1K003_0114, NCTC10702_02013, NCTC13131_00369, NCTC5664_02205, NCTC6133_01555, NCTC7878_01824, NCTC7972_00675, QU38_12725, SAMEA1531744_01573, SAMEA2078260_01474, SAMEA2078588_01661, SAMEA2080344_01643, SAMEA2081063_01322, SAMEA4008575_01811, SAMEA70146418_02592, SAMEA70153168_01835, SAMEA70245418_01921, rpsO, rpsO_1
Sequence domains: Ribosomal protein S15
Small ribosomal subunit protein bS16 Chain: p
Molecule details ›
Chain: p
Length: 89 amino acids
Theoretical weight: 9.99 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8U6K4 (Residues: 2-90; Coverage: 98%)
Gene names: A6760_04900, BN1321_240084, CV021_11345, E1948_05475, E1948_06040, EP54_08595, EQ90_08065, FAF17_11165, G6W63_11660, G6Y24_13750, GO793_08775, GO814_06265, GO941_12470, GO942_07345, GQX37_06910, GZ156_09605, GZ163_05150, HMPREF3211_01282, M1K003_0079, NCTC10702_01954, NCTC13131_00404, NCTC5664_02269, NCTC6133_01505, NCTC7878_01880, NCTC7972_00712, QU38_12530, SAMEA1531744_01538, SAMEA2078260_01509, SAMEA2078588_01626, SAMEA2080344_01678, SAMEA2081063_01357, SAMEA4008575_01846, SAMEA70146418_01672, SAMEA70153168_01800, SAMEA70245418_01958, rpsP, rpsP_1
Sequence domains: Ribosomal protein S16
Small ribosomal subunit protein uS17 Chain: q
Molecule details ›
Chain: q
Length: 80 amino acids
Theoretical weight: 9.37 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077VLD5 (Residues: 5-84; Coverage: 92%)
Gene names: CD116_01845, ERS140147_00629, NCTC13712_02189, rpsQ
Sequence domains: Ribosomal protein S17
Small ribosomal subunit protein bS18 Chain: r
Molecule details ›
Chain: r
Length: 54 amino acids
Theoretical weight: 6.4 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A077UZF4 (Residues: 24-77; Coverage: 68%)
Gene names: CD116_05340, ERS140147_02569, NCTC13712_00314, rpsR
Sequence domains: Ribosomal protein S18
Small ribosomal subunit protein uS19 Chain: s
Molecule details ›
Chain: s
Length: 80 amino acids
Theoretical weight: 9.21 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: A0A133PYC3 (Residues: 20-99; Coverage: 74%)
Gene names: HMPREF3211_01571, rpsS
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein bS20 Chain: t
Molecule details ›
Chain: t
Length: 81 amino acids
Theoretical weight: 8.78 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: W8UXC3 (Residues: 2-82; Coverage: 98%)
Gene names: A6760_01160, BN1321_260224, CV021_16415, E1948_08120, E1948_09560, EP54_13180, EQ90_02045, FAF17_08750, G6W63_07460, G6Y24_01100, GO793_14835, GO814_12840, GO941_07315, GO942_05225, GQX37_10670, GZ156_06525, GZ163_08910, H2639_01455, HMPREF3211_01736, M1K003_1337, NCTC10702_02505, NCTC13131_01905, NCTC5664_03536, NCTC7878_01385, QU38_09005, SAMEA1531744_00187, SAMEA2078260_02721, SAMEA2078588_02759, SAMEA2080344_02727, SAMEA2081063_02772, SAMEA4008575_01402, SAMEA70146418_01084, SAMEA70153168_00278, SAMEA70245418_00840, rpsT, rpsT_1
Sequence domains: Ribosomal protein S20
30S ribosomal protein S21 Chain: u
Molecule details ›
Chain: u
Length: 52 amino acids
Theoretical weight: 6.24 KDa
Source organism: Staphylococcus aureus
Ribosome hibernation promoting factor Chain: v
Molecule details ›
Chain: v
Length: 162 amino acids
Theoretical weight: 18.96 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: D2Z097 (Residues: 2-187; Coverage: 85%)
Gene names: A6760_03745, BN1321_170086, CV021_09125, E1948_01195, E1948_03840, EP54_02760, EQ90_03750, FAF17_02490, G6W63_01690, G6Y24_04360, GO793_15105, GO814_03380, GO941_10480, GO942_03205, GQX37_05310, GZ156_03940, GZ163_03985, H2639_09620, HMPREF3211_01097, M1K003_1172, NCTC13131_00825, NCTC6133_00902, NCTC7878_03405, NCTC7972_01151, QU38_10810, SAMEA1531744_00621, SAMEA2078260_01067, SAMEA2078588_00805, SAMEA2080344_01041, SAMEA2081063_00595, SAMEA4008575_00345, SAMEA70146418_00725, SAMEA70153168_02155, SAMEA70245418_01756, hpf, raiA, yfiA
Sequence domains:
23S ribosomal RNA Chain: A
Molecule details ›
Chain: A
Length: 2905 nucleotides
Theoretical weight: 940.98 KDa
Sequence domains: Bacterial large subunit ribosomal RNA
5S ribosomal RNA Chain: B
Molecule details ›
Chain: B
Length: 115 nucleotides
Theoretical weight: 36.97 KDa
Sequence domains: 5S ribosomal RNA
16S ribosomal RNA Chain: a
Molecule details ›
Chain: a
Length: 1539 nucleotides
Theoretical weight: 498.06 KDa
Sequence domains: Bacterial small subunit ribosomal RNA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.58Å
Relevant EMDB volumes: EMD-10079

Quick links

Citations

5 review citations

Advanced Methods for Studying Structure and Interactions of Macrolide Antibiotics.
Jednačak et al. (2020)
4 more

1 mention without citation

Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Halfon et al. (2019)