› 6qjf

X-ray diffraction
1.5Å resolution

Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group C121, structure 1

Released:
DOI: 10.2210/pdb6qjf/pdb
PDB entry 6qjf coloured by chain, front view.
PDB entry 6qjf coloured by chain, side view.
PDB entry 6qjf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Camara-Artigas A, Murciano-Calles J, Martínez JC
Acta Crystallogr D Struct Biol 75 381-391 (2019)
PMID: 30988255

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160251 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 104 amino acids
Theoretical weight: 11.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P78352 (Residues: 302-403; Coverage: 14%)
Gene names: DLG4, PSD95
Sequence domains: PDZ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 151.9Å b: 31.712Å c: 71.651Å
α: 90° β: 99.51° γ: 90°
R-values:
R R work R free
0.155 0.152 0.199
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

The Conformational Plasticity Vista of PDZ Domains.
Murciano-Calles J. (2020)
2 other articles

2 mentions without citation

Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Gao et al. (2020)
1 more