6pxh

X-ray diffraction
2.3Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-207956 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (7 distinct):
Spike protein S1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 342 amino acids
Theoretical weight: 38.38 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: K9N5Q8 (Residues: 18-351; Coverage: 25%)
Gene names: 3, S
Sequence domains: Betacoronavirus-like spike glycoprotein S1, N-terminal
G2 heavy chain Chains: C, H
Molecule details ›
Chains: C, H
Length: 229 amino acids
Theoretical weight: 24.28 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
G2 light chain Chains: D, L
Molecule details ›
Chains: D, L
Length: 218 amino acids
Theoretical weight: 23.86 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 85.989Å b: 63.86Å c: 186.778Å
α: 90° β: 90.75° γ: 90°
R-values:
R R work R free
0.181 0.18 0.212
Expression system: Homo sapiens