› 6onv

X-ray diffraction
3.25Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Human immunodeficiency virus 1 envelope glycoprotein Gp120 domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 355 amino acids
Theoretical weight: 39.47 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A0M3KKW9 (Residues: 1-353; Coverage: 100%)
Gene name: HIV-1 Env
Sequence domains: Envelope glycoprotein GP120

Ligands and Environments

3 bound ligands:
Ligand NAG 10 x NAG
Ligand MWA 1 x MWA
Ligand EPE 1 x EPE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P212121
Unit cell:
a: 66.256Å b: 67.208Å c: 86.449Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.208 0.265
Expression system: Homo sapiens

Quick links

Citations

3 review citations

The Conformational States of the HIV-1 Envelope Glycoproteins.
Wang et al. (2020)
2 more

2 mentions without citation

A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity.
Ding et al. (2019)
1 more