Function and Biology Details
Reaction catalysed:
Isochorismate + 2-oxoglutarate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161714 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Molecule details ›
Chains: A, B, C, D
Length: 574 amino acids
Theoretical weight: 60.07 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
Sequence domains: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
Length: 574 amino acids
Theoretical weight: 60.07 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
- Canonical:
P9WK11 (Residues: 1-554; Coverage: 100%)
Sequence domains: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
