Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tridecamer (preferred)
Assembly name:
COMA complex (preferred)
PDBe Complex ID:
PDB-CPX-153599 (preferred)
Entry contents:
12 distinct polypeptide molecules
Macromolecules (12 distinct):
Inner kinetochore subunit IML3
Inner kinetochore subunit MCM21
Molecule details ›
Chain: C
Length: 371 amino acids
Theoretical weight: 43.3 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: Cenp-O kinetochore centromere component
Length: 371 amino acids
Theoretical weight: 43.3 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical:
Q06675 (Residues: 1-368; Coverage: 100%)
Sequence domains: Cenp-O kinetochore centromere component
Inner kinetochore subunit CTF19
Inner kinetochore subunit CHL4
Molecule details ›
Chain: E
Length: 461 amino acids
Theoretical weight: 53.02 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: Kinetochore protein CHL4 like
Length: 461 amino acids
Theoretical weight: 53.02 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P38907 (Residues: 1-458; Coverage: 100%)
Sequence domains: Kinetochore protein CHL4 like
Inner kinetochore subunit OKP1
Molecule details ›
Chain: F
Length: 406 amino acids
Theoretical weight: 47.43 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Length: 406 amino acids
Theoretical weight: 47.43 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P53298 (Residues: 1-406; Coverage: 100%)
Inner kinetochore subunit NKP1
Molecule details ›
Chain: G
Length: 241 amino acids
Theoretical weight: 27.28 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Length: 241 amino acids
Theoretical weight: 27.28 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: Q12493 (Residues: 1-238; Coverage: 100%)
Inner kinetochore subunit AME1
Molecule details ›
Chain: I
Length: 330 amino acids
Theoretical weight: 38.34 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: CENPU protein
Length: 330 amino acids
Theoretical weight: 38.34 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P38313 (Residues: 1-324; Coverage: 100%)
Sequence domains: CENPU protein
Inner kinetochore subunit CTF3
Molecule details ›
Chains: H, Y
Length: 773 amino acids
Theoretical weight: 87.77 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Length: 773 amino acids
Theoretical weight: 87.77 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: Q12748 (Residues: 1-733; Coverage: 100%)
Inner kinetochore subunit NKP2
Molecule details ›
Chain: J
Length: 153 amino acids
Theoretical weight: 17.88 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: Cnl2/NKP2 family protein
Length: 153 amino acids
Theoretical weight: 17.88 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: Q06162 (Residues: 1-153; Coverage: 100%)
Sequence domains: Cnl2/NKP2 family protein
