› 6lfq

X-ray diffraction
2.36Å resolution

Crystal structure of Poa1p in apo form

Released:
DOI: 10.2210/pdb6lfq/pdb
PDB entry 6lfq coloured by chain, front view.
PDB entry 6lfq coloured by chain, side view.
PDB entry 6lfq coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Expanding the Substrate Specificity of Macro Domains toward 3''-Isomer of O-Acetyl-ADP-ribose
Chiu YC, Tseng MC, Hsu CH
ACS Catalysis 11 11075-11090 (2021)

Function and Biology Details

Reaction catalysed: 
ADP-D-ribose 1''-phosphate + H(2)O = ADP-D-ribose + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153584 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribose 1''-phosphate phosphatase Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 20.24 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P38218 (Residues: 1-177; Coverage: 100%)
Gene names: POA1, YBR022W, YBR0304
Sequence domains: Macro domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE TPS 05A
Spacegroup: I222
Unit cell:
a: 49.195Å b: 59.612Å c: 100.658Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.16 0.255
Expression system: Escherichia coli

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