› 6l7k

Solution NMR

solution structure of hIFABP V60C/Y70C variant.

Released:
DOI: 10.2210/pdb6l7k/pdb
PDB entry 6l7k coloured by chain, ensemble of 20 models, front view.
PDB entry 6l7k coloured by chain, ensemble of 20 models, side view.
PDB entry 6l7k coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Ligand Entry into Fatty Acid Binding Protein via Local Unfolding Instead of Gap Widening.
Xiao T, Lu Y, Fan JS, Yang D
Biophys J 118 396-402 (2020)
PMID: 31870540

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146097 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, intestinal Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 15.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P12104 (Residues: 2-132; Coverage: 99%)
Gene names: FABP2, FABPI
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 76%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Fatty Acid-Binding Proteins in Psoriasis-A Review.
Nowowiejska et al. (2022)
6 other articles

1 mention without citation

Ligand Entry into Fatty Acid Binding Protein via Local Unfolding Instead of Gap Widening.
Xiao et al. (2020)