› 6kvg

Solution NMR

The solution structure of human Orc6

Released:
DOI: 10.2210/pdb6kvg/pdb
PDB entry 6kvg coloured by chain, ensemble of 20 models, front view.
PDB entry 6kvg coloured by chain, ensemble of 20 models, side view.
PDB entry 6kvg coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA.
Xu N, You Y, Liu C, Balasov M, Lun LT, Geng Y, Fung CP, Miao H, Tian H, Choy TT, Shi X, Fan Z, Zhou B, Akhmetova K, Din RU, Yang H, Hao Q, Qian P, Chesnokov I, Zhu G
Nucleic Acids Res 48 11146-11161 (2020)
PMID: 32986843

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195279 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Origin recognition complex subunit 6 Chain: A
Molecule details ›
Chain: A
Length: 256 amino acids
Theoretical weight: 28.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y5N6 (Residues: 1-252; Coverage: 100%)
Gene names: ORC6, ORC6L
Sequence domains: Origin recognition complex subunit 6 (ORC6)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Expansion and Functional Diversification of TFIIB-Like Factors in Plants.
Ning et al. (2021)
9 other articles

1 mention without citation

Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA.
Xu et al. (2020)