› 6kjo

Solution NMR

The microtubule-binding domains of yeast cytoplasmic dynein in the low affinity state

Released:
DOI: 10.2210/pdb6kjo/pdb
PDB entry 6kjo coloured by chain, ensemble of 10 models, front view.
PDB entry 6kjo coloured by chain, ensemble of 10 models, side view.
PDB entry 6kjo coloured by chain, ensemble of 10 models, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Structural basis for two-way communication between dynein and microtubules.
Nishida N, Komori Y, Takarada O, Watanabe A, Tamura S, Kubo S, Shimada I, Kikkawa M
Nat Commun 11 1038 (2020)
PMID: 32098965

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153103 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynein heavy chain, cytoplasmic Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 16.53 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P36022 (Residues: 3095-3232; Coverage: 3%)
Gene names: DHC1, DYN1, YKR054C
Sequence domains: Microtubule-binding stalk of dynein motor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 71%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structure and Mechanics of Dynein Motors.
Canty et al. (2021)
1 more