Function and Biology Details
Reaction catalysed:
Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Ribosomal protein eL8/Nhp2 family
- Ribosomal protein eL30-like superfamily
- Large ribosomal subunit protein eL8, archaea
- Ribonuclease P subunit RNP4
- Ribonuclease P protein subunit Rpp29/RNP1
- RNase P subunit Pop5/Rpp14/Rnp2-like
- RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily
- Large ribosomal subunit protein eL8-like, conserved site
11 more domains
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-156937 (preferred)
Entry contents:
5 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (6 distinct):
Ribonuclease P protein component 2
Molecule details ›
Chains: A, B
Length: 134 amino acids
Theoretical weight: 15.97 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Rpp14/Pop5 family
Length: 134 amino acids
Theoretical weight: 15.97 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q57917 (Residues: 1-134; Coverage: 100%)
Sequence domains: Rpp14/Pop5 family
Ribonuclease P protein component 3
Molecule details ›
Chains: C, D
Length: 232 amino acids
Theoretical weight: 27.39 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: RNase P subunit p30
Length: 232 amino acids
Theoretical weight: 27.39 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q58539 (Residues: 1-232; Coverage: 100%)
Sequence domains: RNase P subunit p30
Ribonuclease P protein component 1
Molecule details ›
Chains: E, F
Length: 95 amino acids
Theoretical weight: 10.91 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Ribonuclease P/MRP, subunit p29
Length: 95 amino acids
Theoretical weight: 10.91 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q57903 (Residues: 1-95; Coverage: 100%)
Sequence domains: Ribonuclease P/MRP, subunit p29
Ribonuclease P protein component 4
Molecule details ›
Chains: G, H
Length: 128 amino acids
Theoretical weight: 15.61 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: RNAse P Rpr2/Rpp21/SNM1 subunit domain
Length: 128 amino acids
Theoretical weight: 15.61 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q58372 (Residues: 1-128; Coverage: 100%)
Sequence domains: RNAse P Rpr2/Rpp21/SNM1 subunit domain
Large ribosomal subunit protein eL8
Molecule details ›
Chains: I, J
Length: 117 amino acids
Theoretical weight: 12.7 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Length: 117 amino acids
Theoretical weight: 12.7 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P54066 (Residues: 1-117; Coverage: 100%)
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
