› 6jl7

X-ray diffraction
2.5Å resolution

crystal structure of TBC1D23 N terminal domain

Released:
DOI: 10.2210/pdb6jl7/pdb
PDB entry 6jl7 coloured by chain, front view.
PDB entry 6jl7 coloured by chain, side view.
PDB entry 6jl7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain.
Liu D, Yang F, Liu Z, Wang J, Huang W, Meng W, Billadeau DD, Sun Q, Mo X, Jia D
PLoS Biol 18 e3000746 (2020)
PMID: 32453802

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192626 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TBC1 domain family member 23 Chain: A
Molecule details ›
Chain: A
Length: 444 amino acids
Theoretical weight: 50.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NUY8 (Residues: 17-460; Coverage: 64%)
Gene names: NS4ATP1, TBC1D23
Sequence domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P65
Unit cell:
a: 151.736Å b: 151.736Å c: 38.604Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.219 0.217 0.252
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Targeting Endosomal Recycling Pathways by Bacterial and Viral Pathogens.
Yong et al. (2021)
6 other articles

1 mention without citation

Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain.
Liu et al. (2020)