› 6ji4

X-ray diffraction
1.6Å resolution

brd4-bd1 bound with ligand 138

Released:
DOI: 10.2210/pdb6ji4/pdb
PDB entry 6ji4 coloured by chain, front view.
PDB entry 6ji4 coloured by chain, side view.
PDB entry 6ji4 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Cao DY, Li YL, Du ZY, Li J, Xiong B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130112 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 4 Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60885 (Residues: 44-166; Coverage: 9%)
Gene names: BRD4, HUNK1
Sequence domains: Bromodomain

Ligands and Environments

1 bound ligand:
Ligand BOF 1 x BOF
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 35.31Å b: 47.649Å c: 77.562Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.231
Expression system: Escherichia coli

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