› 6hy4

X-ray diffraction
1.83Å resolution

Co(II)-substituted Wells-Dawson binding to Hen Egg-White Lysozyme (HEWL)

Released:
DOI: 10.2210/pdb6hy4/pdb
PDB entry 6hy4 coloured by chain, front view.
PDB entry 6hy4 coloured by chain, side view.
PDB entry 6hy4 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Noncovalent Complexes Formed between Metal-Substituted Polyoxometalates and Hen Egg White Lysozyme
Vandebroek L, Mampaey Y, Antonyuk S, Van Meervelt L, Parac-Vogt TN
Eur. J. inorg. Chem. (2019)

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132831 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 128 amino acids
Theoretical weight: 14.22 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P00698 (Residues: 19-146; Coverage: 99%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family

Ligands and Environments

2 bound ligands:
Ligand CWO 1 x CWO
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P43212
Unit cell:
a: 78.734Å b: 78.734Å c: 37.179Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.214

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