6fxl

X-ray diffraction
1.96Å resolution

Structure of Trypanosoma cruzi type B ribose 5-phosphate isomerase (TcRpiB)

Released:
Entry authors: Ronin C, Ciesielski F, Ciapetti P

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-175470 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribose 5-phosphate isomerase, putative Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 179 amino acids
Theoretical weight: 19.52 KDa
Source organism: Trypanosoma cruzi strain CL Brener
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4DBP9 (Residues: 1-159; Coverage: 100%)
Gene name: Tc00.1047053508601.119
Sequence domains: Ribose/Galactose Isomerase
Structure domains: Sugar-phosphate isomerase, RpiB/LacA/LacB

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: C2221
Unit cell:
a: 171.16Å b: 175.35Å c: 93.27Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.162 0.161 0.184
Expression system: Escherichia coli