› 6fqe

X-ray diffraction
1.75Å resolution

Phosphotriesterase PTE_A53_4

Released:
DOI: 10.2210/pdb6fqe/pdb
PDB entry 6fqe coloured by chain, front view.
PDB entry 6fqe coloured by chain, side view.
PDB entry 6fqe coloured by chain, top view.
Source organism: Brevundimonas diminuta
Entry authors: Dym O, Aggarwal N, Albeck S, Unger T, Hamer Rogotner S, Silman I, Leader H, Ashani Y, Goldsmith M, Greisen P, Tawfik D, Sussman LJ

Function and Biology Details

Reaction catalysed: 
An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141250 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Parathion hydrolase Chain: A
Molecule details ›
Chain: A
Length: 340 amino acids
Theoretical weight: 36.76 KDa
Source organism: Brevundimonas diminuta
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A434 (Residues: 34-365; Coverage: 99%)
Gene name: opd
Sequence domains: Phosphotriesterase family
Structure domains: Metal-dependent hydrolases
Parathion hydrolase Chain: B
Molecule details ›
Chain: B
Length: 340 amino acids
Theoretical weight: 36.76 KDa
Source organism: Brevundimonas diminuta
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A434 (Residues: 34-365; Coverage: 99%)
Gene name: opd
Sequence domains: Phosphotriesterase family
Structure domains: Metal-dependent hydrolases

Ligands and Environments

4 bound ligands:
Ligand FMT 2 x FMT
Ligand ZN 4 x ZN
Ligand D6K 2 x D6K
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 54.55Å b: 81.3Å c: 70.61Å
α: 90° β: 94.96° γ: 90°
R-values:
R R work R free
0.161 0.16 0.186
Expression system: Escherichia coli

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