6f8d

X-ray diffraction
3.48Å resolution

Crystal structure of Human ARS2 residues 171-270 + 408-763 (P65 form)

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-189796 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serrate RNA effector molecule homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 100 amino acids
Theoretical weight: 12.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BXP5 (Residues: 171-270; Coverage: 11%)
Gene names: ARS2, ASR2, SRRT
Sequence domains: SERRATE/Ars2, N-terminal domain
Serrate RNA effector molecule homolog Chains: C, D
Molecule details ›
Chains: C, D
Length: 356 amino acids
Theoretical weight: 41.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BXP5 (Residues: 409-764; Coverage: 41%)
Gene names: ARS2, ASR2, SRRT
Sequence domains: Arsenite-resistance protein 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P65
Unit cell:
a: 105.21Å b: 105.21Å c: 267.04Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.265 0.264 0.292
Expression system: Escherichia coli BL21(DE3)