› 6esp

Solution NMR

Proteome-wide analysis of phospho-regulated PDZ domain interactions

Released:
DOI: 10.2210/pdb6esp/pdb
PDB entry 6esp coloured by chain, ensemble of 20 models, front view.
PDB entry 6esp coloured by chain, ensemble of 20 models, side view.
PDB entry 6esp coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Proteome-wide analysis of phospho-regulated PDZ domain interactions.
Sundell GN, Arnold R, Ali M, Naksukpaiboon P, Orts J, Güntert P, Chi CN, Ivarsson Y
Mol Syst Biol 14 e8129 (2018)
PMID: 30126976

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171945 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein scribble homolog Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 12.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14160 (Residues: 719-829; Coverage: 7%)
Gene names: CRIB1, KIAA0147, LAP4, SCRB1, SCRIB, VARTUL
Sequence domains: PDZ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 53%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Specificity in PDZ-peptide interaction networks: Computational analysis and review.
Amacher et al. (2020)
6 more

1 mention without citation

Proteome-wide analysis of phospho-regulated PDZ domain interactions.
Sundell et al. (2018)