› 6e2x

Electron Microscopy
3.5Å resolution

Mechanism of cellular recognition by PCV2

Released:
DOI: 10.2210/pdb6e2x/pdb
PDB entry 6e2x coloured by chain, front view.
PDB entry 6e2x coloured by chain, side view.
PDB entry 6e2x coloured by chain, top view.
Source organism: Porcine circovirus 2
Primary publication:
Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid.
Dhindwal S, Avila B, Feng S, Khayat R
J Virol 93 (2019)
PMID: 30602608
Related structures: EMD-8970

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182335 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Cap protein Chains: A1, A2, A3, A4, A5, A6, A7, A8, A9, AA, AB, AC, AD, AE, AF, AG, AH, AI, AJ, AK, AL, AM, AN, AO, AP, AQ, AR, AS, AT, AU, AV, AW, AX, AY, AZ, Aa, Ab, Ac, Ad, Ae, Af, Ag, Ah, Ai, Aj, Ak, Al, Am, An, Ao, Ap, Aq, Ar, As, At, Au, Av, Aw, Ax, Ay
Molecule details ›
Chains: A1, A2, A3, A4, A5, A6, A7, A8, A9, AA, AB, AC, AD, AE, AF, AG, AH, AI, AJ, AK, AL, AM, AN, AO, AP, AQ, AR, AS, AT, AU, AV, AW, AX, AY, AZ, Aa, Ab, Ac, Ad, Ae, Af, Ag, Ah, Ai, Aj, Ak, Al, Am, An, Ao, Ap, Aq, Ar, As, At, Au, Av, Aw, Ax, Ay
Length: 233 amino acids
Theoretical weight: 27.9 KDa
Source organism: Porcine circovirus 2
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q805N7 (Residues: 1-233; Coverage: 100%)
Gene names: Cap, ORF2, PCV2_gp3, cap, cp
Sequence domains: Circovirus capsid protein

Ligands and Environments

Carbohydrate polymer : NEW Components: SGN, IDS
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-8970
Expression system: Trichoplusia ni

Quick links

Citations

3 review citations

Current knowledge on epidemiology and evolution of novel porcine circovirus 4.
Wang et al. (2022)
2 more

1 mention without citation

Porcine Circovirus 2 Uses a Multitude of Weak Binding Sites To Interact with Heparan Sulfate, and the Interactions Do Not Follow the Symmetry of the Capsid.
Dhindwal et al. (2019)