Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138544 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cAMP-dependent protein kinase catalytic subunit alpha
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 41.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 356 amino acids
Theoretical weight: 41.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P05132 (Residues: 2-351; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
cAMP-dependent protein kinase inhibitor alpha
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 20 amino acids
Theoretical weight: 2.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P61925 (Residues: 6-25; Coverage: 26%)
Ligands and Environments
Experiments and Validation Details
Experimental Method:
X-ray diffraction, Neutron Diffraction
X-ray source:
RIGAKU MICROMAX-007 HF, ILL BEAMLINE LADI III
Spacegroup:
P212121
Expression systems:
- Escherichia coli
- Not provided
