6dzq

X-ray diffraction
2.25Å resolution

The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-111233 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase acidic protein Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 22.47 KDa
Source organism: Influenza A virus (A/California/04/2009(H1N1))
Expression system: Escherichia coli
UniProt:
  • Canonical: C3W5S0 (Residues: 1-198; Coverage: 26%)
Gene name: PA
Structure domains: Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P6222
Unit cell:
a: 75.2Å b: 75.2Å c: 119.62Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.205 0.253
Expression system: Escherichia coli