› 6d4i

X-ray diffraction
2.95Å resolution

Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG2

Released:
DOI: 10.2210/pdb6d4i/pdb
PDB entry 6d4i coloured by chain, front view.
PDB entry 6d4i coloured by chain, side view.
PDB entry 6d4i coloured by chain, top view.
Source organism: Macaca mulatta
Primary publication:
From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Tolbert WD, Subedi GP, Gohain N, Lewis GK, Patel KR, Barb AW, Pazgier M
MAbs 11 709-724
PMID: 30939981

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123663 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ig-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 223 amino acids
Theoretical weight: 25.08 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
UniProt:
  • Canonical: F7H602 (Residues: 1-194; Coverage: 73%)
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P32
Unit cell:
a: 66.916Å b: 66.916Å c: 87.454Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.207 0.261
Expression system: Homo sapiens

Quick links

Citations

1 review citation

A synopsis of recent developments defining how N-glycosylation impacts immunoglobulin G structure and function.
Yamaguchi et al. (2020)
11 other articles

1 mention without citation

From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Tolbert et al. (2019)