› 6cgh

Solution NMR

Solution structure of the four-helix bundle region of human J-protein Zuotin, a component of ribosome-associated complex (RAC)

Released:
DOI: 10.2210/pdb6cgh/pdb
PDB entry 6cgh coloured by chain, ensemble of 20 models, front view.
PDB entry 6cgh coloured by chain, ensemble of 20 models, side view.
PDB entry 6cgh coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70.
Shrestha OK, Sharma R, Tomiczek B, Lee W, Tonelli M, Cornilescu G, Stolarska M, Nierzwicki L, Czub J, Markley JL, Marszalek J, Ciesielski SJ, Craig EA
PLoS One 14 e0217098 (2019)
PMID: 31091298

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189217 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DnaJ homolog subfamily C member 2, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99543 (Residues: 346-432; Coverage: 14%)
Gene names: DNAJC2, MPHOSPH11, MPP11, ZRF1
Sequence domains: Ribosome-associated complex head domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 73%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural and functional analysis of the Hsp70/Hsp40 chaperone system.
Liu et al. (2020)
4 other articles

1 mention without citation

Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70.
Shrestha et al. (2019)