› 6c15

X-ray diffraction
3.21Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151327 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T-cell surface glycoprotein CD1c Chain: A
Molecule details ›
Chain: A
Length: 287 amino acids
Theoretical weight: 32.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P29017 (Residues: 19-297; Coverage: 88%)
Gene name: CD1C
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 108 amino acids
Theoretical weight: 12.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

8 bound ligands:
Ligand NAG 3 x NAG
Ligand D12 1 x D12
Ligand 6PL 1 x 6PL
Ligand NA 1 x NA
Ligand SO4 1 x SO4
Ligand BME 1 x BME
Ligand EDO 1 x EDO
Ligand MES 1 x MES
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P6522
Unit cell:
a: 84.255Å b: 84.255Å c: 366.833Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.208 0.242
Expression system: Homo sapiens

Quick links

Citations

9 review citations

A multilayered immune system through the lens of unconventional T cells.
Mayassi et al. (2021)
8 more

4 mentions without citation

Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity.
Shahine et al. (2021)
3 more