› 6bxf

X-ray diffraction
3.2Å resolution

Crystal structure of an extended b3 integrin L33

Released:
DOI: 10.2210/pdb6bxf/pdb
PDB entry 6bxf coloured by chain, front view.
PDB entry 6bxf coloured by chain, side view.
PDB entry 6bxf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of an extended β3 integrin.
Zhou D, Thinn AMM, Zhao Y, Wang Z, Zhu J
Blood 132 962-972 (2018)
PMID: 30018079

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-L; Integrin beta-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 466 amino acids
Theoretical weight: 51.97 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P05106 (Residues: 27-135, 378-548; Coverage: 37%)
  • Canonical: P20701 (Residues: 153-331; Coverage: 16%)
Gene names: CD11A, GP3A, ITGAL, ITGB3
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand GOL 2 x GOL
Ligand NAG 7 x NAG
Ligand CA 1 x CA
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 59.07Å b: 81.47Å c: 127.96Å
α: 90° β: 97.07° γ: 90°
R-values:
R R work R free
0.268 0.265 0.335
Expression system: Homo sapiens

Quick links

Citations

2 review citations

Structural Immunology of Complement Receptors 3 and 4.
Vorup-Jensen et al. (2018)
1 more

1 mention without citation

Structure of an extended β3 integrin.
Zhou et al. (2018)