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X-ray diffraction
1.96Å resolution

Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-137525 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H-2 class II histocompatibility antigen, A-D alpha chain Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 20.9 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P04228 (Residues: 26-208; Coverage: 79%)
Gene name: H2-Aa
Sequence domains:
Structure domains:
Ig-like domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 25.36 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q31135 (Residues: 21-217; Coverage: 77%)
Gene name: H2-Ab1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2221
Unit cell:
a: 89.736Å b: 111.379Å c: 95.275Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.228
Expression system: Trichoplusia ni