› 6bih

Electron Microscopy
6Å resolution

The Structure of the Actin-Smooth Muscle Myosin Motor Domain Complex in the Rigor State

Released:
DOI: 10.2210/pdb6bih/pdb
PDB entry 6bih coloured by chain, front view.
PDB entry 6bih coloured by chain, side view.
PDB entry 6bih coloured by chain, top view.
Source organisms:
Primary publication:
The structure of the actin-smooth muscle myosin motor domain complex in the rigor state.
Banerjee C, Hu Z, Huang Z, Warrington JA, Taylor DW, Trybus KM, Lowey S, Taylor KA
J Struct Biol 200 325-333 (2017)
PMID: 29038012
Related structures: EMD-7100

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetradecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145343 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Myosin-11 Chain: H
Molecule details ›
Chain: H
Length: 798 amino acids
Theoretical weight: 91.34 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P10587 (Residues: 1-790; Coverage: 40%)
Gene name: MYH11
Sequence domains:
Actin, alpha skeletal muscle Chain: C
Molecule details ›
Chain: C
Length: 377 amino acids
Theoretical weight: 42.1 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 1-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Sequence domains: Actin

Ligands and Environments

2 bound ligands:
Ligand ADP 1 x ADP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6Å
Relevant EMDB volumes: EMD-7100
Expression system: Spodoptera frugiperda

Quick links

Citations

3 review citations

Classifying Cardiac Actin Mutations Associated With Hypertrophic Cardiomyopathy.
Despond et al. (2018)
2 more

2 mentions without citation

The structure of the actin-smooth muscle myosin motor domain complex in the rigor state.
Banerjee et al. (2017)
1 more