› 6b9b

X-ray diffraction
1.8Å resolution

Crystal structure of the catalase-peroxidase from B. pseudomallei with maltose bound

Released:
DOI: 10.2210/pdb6b9b/pdb
PDB entry 6b9b coloured by chain, front view.
PDB entry 6b9b coloured by chain, side view.
PDB entry 6b9b coloured by chain, top view.
Source organism: Burkholderia pseudomallei 1710b
Primary publication:
KatG-Mediated Oxidation Leading to Reduced Susceptibility of Bacteria to Kanamycin.
Loewen PC, De Silva PM, Donald LJ, Switala J, Villanueva J, Fita I, Kumar A
ACS Omega 3 4213-4219 (2018)
PMID: 29732452

Function and Biology Details

Reaction catalysed: 
2 H(2)O(2) = O(2) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174650 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Catalase-peroxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 728 amino acids
Theoretical weight: 79.57 KDa
Source organism: Burkholderia pseudomallei 1710b
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3JNW6 (Residues: 1-728; Coverage: 100%)
Gene names: BURPS1710b_3366, katG
Sequence domains: Peroxidase
Structure domains:

Ligands and Environments


Cofactor: Ligand HEM 2 x HEM
Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
5 bound ligands:
Ligand NA 2 x NA
Ligand CL 2 x CL
Ligand OXY 2 x OXY
Ligand PO4 2 x PO4
Ligand MPD 3 x MPD
1 modified residue:
Ligand TOX 2 x TOX

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 100.419Å b: 115.088Å c: 174.975Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.137 0.135 0.162
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Better together-Salmonella biofilm-associated antibiotic resistance.
Aleksandrowicz et al. (2023)
6 other articles

1 mention without citation

Local and global analysis of macromolecular atomic displacement parameters.
Masmaliyeva et al. (2020)