6b7g

Solution NMR

Solution NMR structure of BCoR in complex with AF9 (BCoR-AF9)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-154677 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein AF-9 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42568 (Residues: 500-568; Coverage: 12%)
Gene names: AF9, MLLT3, YEATS3
Sequence domains: ANC1 homology domain (AHD)
BCL-6 corepressor Chain: B
Molecule details ›
Chain: B
Length: 33 amino acids
Theoretical weight: 3.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6W2J9 (Residues: 1176-1207; Coverage: 2%)
Gene names: BCOR, KIAA1575

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Expression system: Escherichia coli