› 6b26

X-ray diffraction
1.2Å resolution

Crystal structure of human STAC2 Tandem SH3 Domains (296-411)

Released:
DOI: 10.2210/pdb6b26/pdb
PDB entry 6b26 coloured by chain, front view.
PDB entry 6b26 coloured by chain, side view.
PDB entry 6b26 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Wong King Yuen SM, Campiglio M, Tung CC, Flucher BE, Van Petegem F
Proc Natl Acad Sci U S A 114 E9520-E9528 (2017)
PMID: 29078335

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180578 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SH3 and cysteine-rich domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6ZMT1 (Residues: 296-411; Coverage: 28%)
Gene name: STAC2
Sequence domains:
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 36.857Å b: 47.993Å c: 73.587Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.153 0.152 0.169
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Skeletal muscle CaV1.1 channelopathies.
Flucher BE. (2020)
8 more

1 mention without citation

Structural insights into binding of STAC proteins to voltage-gated calcium channels.
Wong King Yuen et al. (2017)