› 6axx

X-ray diffraction
2.6Å resolution

Structure of the T58A/I124A mutant of the HIV-1 capsid protein

Released:
DOI: 10.2210/pdb6axx/pdb
PDB entry 6axx coloured by chain, front view.
PDB entry 6axx coloured by chain, side view.
PDB entry 6axx coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Entry authors: Gres AT, Kirby KA, Sarafianos SG

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146190 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein p24 Chain: A
Molecule details ›
Chain: A
Length: 231 amino acids
Theoretical weight: 25.56 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12493 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand IOD 8 x IOD
Ligand CL 9 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P6
Unit cell:
a: 91.646Å b: 91.646Å c: 57.695Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.19 0.246
Expression system: Escherichia coli BL21(DE3)

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