› 6a59

X-ray diffraction
1.82Å resolution

Structure of histone demethylase REF6 at 1.8A

Released:
DOI: 10.2210/pdb6a59/pdb
PDB entry 6a59 coloured by chain, front view.
PDB entry 6a59 coloured by chain, side view.
PDB entry 6a59 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms.
Tian Z, Li X, Li M, Wu W, Zhang M, Tang C, Li Z, Liu Y, Chen Z, Yang M, Ma L, Caba C, Tong Y, Lam HM, Dai S, Chen Z
Cell Discov 6 17 (2020)
PMID: 32257379

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193536 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase REF6 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 16.52 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9STM3 (Residues: 1223-1360; Coverage: 10%)
Gene names: At3g48430, EIN6, JMJ12, PKDM9A, REF6, T29H11_50

Ligands and Environments

1 bound ligand:
Ligand ZN 4 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NFPSS BEAMLINE BL18U
Spacegroup: P41
Unit cell:
a: 63.445Å b: 63.445Å c: 43.533Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.215 0.23
Expression system: Escherichia coli

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Citations

4 review citations

Dynamics of H3K27me3 Modification on Plant Adaptation to Environmental Cues.
Shen et al. (2021)
3 more