Function and Biology Details
Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- V-ATPase proteolipid subunit
- F/V-ATP synthase subunit C superfamily
- V-ATPase proteolipid subunit C-like domain
- V-type ATP synthase regulatory subunit B/beta
- P-loop containing nucleoside triphosphate hydrolase
- ATPase, alpha/beta subunit, nucleotide-binding domain, active site
- ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
- ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
19 more domains
Structure analysis Details
Assembly composition:
hetero 26-mer (preferred)
PDBe Complex ID:
PDB-CPX-131510 (preferred)
Entry contents:
9 distinct polypeptide molecules
Macromolecules (9 distinct):
V-type ATP synthase alpha chain
Molecule details ›
Chains: A, B, C
Length: 578 amino acids
Theoretical weight: 63.7 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains:
Length: 578 amino acids
Theoretical weight: 63.7 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical:
Q56403 (Residues: 1-578; Coverage: 100%)
Sequence domains:
V-type ATP synthase beta chain
Molecule details ›
Chains: D, E, F
Length: 478 amino acids
Theoretical weight: 53.22 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains:
Length: 478 amino acids
Theoretical weight: 53.22 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q56404 (Residues: 1-478; Coverage: 100%)
Sequence domains:
V-type ATP synthase subunit D
Molecule details ›
Chain: G
Length: 223 amino acids
Theoretical weight: 24.72 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains: ATP synthase subunit D
Length: 223 amino acids
Theoretical weight: 24.72 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: O87880 (Residues: 1-223; Coverage: 100%)
Sequence domains: ATP synthase subunit D
V-type ATP synthase subunit F
Molecule details ›
Chain: H
Length: 104 amino acids
Theoretical weight: 11.29 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains: ATP synthase (F/14-kDa) subunit
Length: 104 amino acids
Theoretical weight: 11.29 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: P74903 (Residues: 1-104; Coverage: 100%)
Sequence domains: ATP synthase (F/14-kDa) subunit
V-type ATP synthase, subunit (VAPC-THERM)
Molecule details ›
Chains: I, K
Length: 120 amino acids
Theoretical weight: 13.17 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains: Vacuolar (H+)-ATPase G subunit
Length: 120 amino acids
Theoretical weight: 13.17 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q5SIT5 (Residues: 1-120; Coverage: 100%)
Sequence domains: Vacuolar (H+)-ATPase G subunit
V-type ATP synthase subunit E
Molecule details ›
Chains: J, L
Length: 188 amino acids
Theoretical weight: 20.7 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains: ATP synthase (E/31 kDa) subunit
Length: 188 amino acids
Theoretical weight: 20.7 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: P74901 (Residues: 1-188; Coverage: 100%)
Sequence domains: ATP synthase (E/31 kDa) subunit
V-type ATP synthase subunit C
Molecule details ›
Chain: M
Length: 323 amino acids
Theoretical weight: 35.97 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains: ATP synthase (C/AC39) subunit
Length: 323 amino acids
Theoretical weight: 35.97 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: P74902 (Residues: 1-323; Coverage: 100%)
Sequence domains: ATP synthase (C/AC39) subunit
V-type ATP synthase subunit I
Molecule details ›
Chain: N
Length: 652 amino acids
Theoretical weight: 72.2 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains:
Length: 652 amino acids
Theoretical weight: 72.2 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q5SIT6 (Residues: 1-652; Coverage: 100%)
Sequence domains:
V-ATPase proteolipid subunit C-like domain-containing protein
Molecule details ›
Chains: O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 99 amino acids
Theoretical weight: 9.84 KDa
Source organism: Thermus thermophilus HB8
UniProt:
Sequence domains: ATP synthase subunit C
Length: 99 amino acids
Theoretical weight: 9.84 KDa
Source organism: Thermus thermophilus HB8
UniProt:
- Canonical: Q5SIT7 (Residues: 1-99; Coverage: 100%)
Sequence domains: ATP synthase subunit C
