› 5xf7

X-ray diffraction
2.38Å resolution

Crystal structure of human protein disulfide isomerase-like protein of the testis

Released:
DOI: 10.2210/pdb5xf7/pdb
PDB entry 5xf7 coloured by chain, front view.
PDB entry 5xf7 coloured by chain, side view.
PDB entry 5xf7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity.
Li H, Yang K, Wang W, Niu Y, Li J, Dong Y, Liu Y, Wang CC, Wang L, Liang H
J Biol Chem 293 1192-1202 (2018)
PMID: 29203529

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185432 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase-like protein of the testis Chain: A
Molecule details ›
Chain: A
Length: 579 amino acids
Theoretical weight: 66.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8N807 (Residues: 6-6, 21-584; Coverage: 98%)
Gene name: PDILT
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P32
Unit cell:
a: 97.361Å b: 97.361Å c: 57.588Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.197 0.235
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The Role of Protein S-Nitrosylation in Protein Misfolding-Associated Diseases.
Ju et al. (2021)
3 other articles

3 mentions without citation

Allosteric modulation of G protein-coupled receptor signaling.
Shen et al. (2023)
2 more