Function and Biology Details
Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid
Endonucleolytic cleavage to 5'-phosphomonoester.
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Integrase (preferred)
PDBe Complex ID:
PDB-CPX-153061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrase
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 25.61 KDa
Source organism: Visna-maedi virus
Expression system: Escherichia coli
UniProt:
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
Length: 222 amino acids
Theoretical weight: 25.61 KDa
Source organism: Visna-maedi virus
Expression system: Escherichia coli
UniProt:
- Canonical:
P35956 (Residues: 1285-1506; Coverage: 15%)
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
