› 5rka

X-ray diffraction
1.33Å resolution

PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z126932614

Released:
DOI: 10.2210/pdb5rka/pdb
PDB entry 5rka coloured by chain, front view.
PDB entry 5rka coloured by chain, side view.
PDB entry 5rka coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Grosjean H, Aimon A, Krojer T, Talon R, Douangamath A, Koekemoer L, Arrowsmith CH, Edwards A, Bountra C, von Delft F, Biggin PC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186760 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PH-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 17.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WWQ0 (Residues: 1315-1440; Coverage: 7%)
Gene names: DCAF14, PHIP, WDR11
Sequence domains: Bromodomain

Ligands and Environments

1 bound ligand:
Ligand T6J 1 x T6J
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2
Unit cell:
a: 82.36Å b: 27Å c: 55.56Å
α: 90° β: 99.73° γ: 90°
R-values:
R R work R free
0.192 0.19 0.221
Expression system: Escherichia coli

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