› 5owp

X-ray diffraction
1.85Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208480 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig heavy chain V-III region J606; Ig lambda-1 chain V region H2020 Chain: H
Molecule details ›
Chain: H
Length: 244 amino acids
Theoretical weight: 25.76 KDa
Source organism: Mus musculus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P01801 (Residues: 6-99, 100-111; Coverage: 92%)
  • Canonical: P01726 (Residues: 19-129; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE Chain: D
Molecule details ›
Chain: D
Length: 8 amino acids
Theoretical weight: 833 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand EDO 3 x EDO
Ligand A2G 1 x A2G
1 modified residue:
Ligand 4FB 1 x 4FB

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 35.399Å b: 68.151Å c: 90.358Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.194 0.256
Expression systems:
  • Komagataella pastoris
  • Not provided

Quick links

Citations

3 review citations

Glycans in drug discovery.
Valverde et al. (2019)
2 more

2 mentions without citation

Molecular Recognition of GalNAc in Mucin-Type O-Glycosylation.
Sanz-Martinez et al. (2023)
1 more