Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Neurotransmitter-gated ion-channel
- Gamma-aminobutyric acid A receptor/Glycine receptor alpha
- Neurotransmitter-gated ion-channel ligand-binding domain superfamily
- Neurotransmitter-gated ion-channel transmembrane domain
- Neuronal acetylcholine receptor
- Gamma-aminobutyric acid receptor subunit alpha 1-6, transmembrane domain
- Neurotransmitter-gated ion-channel transmembrane domain superfamily
- Neurotransmitter-gated ion-channel ligand-binding domain
Structure analysis Details
Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-242312 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-aminobutyric acid receptor subunit alpha-1; Gamma-aminobutyric acid receptor subunit alpha-2; Proton-gated ion channel
Molecule details ›
Chains: A, B, C, D, E
Length: 336 amino acids
Theoretical weight: 38.64 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 336 amino acids
Theoretical weight: 38.64 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q7NDN8 (Residues: 44-236, 270-271; Coverage: 62%) - Canonical: P26048 (Residues: 251-285, 288-339, 416-419; Coverage: 22%)
- Canonical: P62812 (Residues: 421-455; Coverage: 8%)
Sequence domains:
- Neurotransmitter-gated ion-channel ligand binding domain
- Neurotransmitter-gated ion-channel transmembrane region
