› 5o0n

X-ray diffraction
2.5Å resolution

Deglycosylated Nogo Receptor with native disulfide structure 4

Released:
DOI: 10.2210/pdb5o0n/pdb
PDB entry 5o0n coloured by chain, front view.
PDB entry 5o0n coloured by chain, side view.
PDB entry 5o0n coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction.
Pronker MF, Tas RP, Vlieg HC, Janssen BJC
Acta Crystallogr D Struct Biol 73 860-876 (2017)
PMID: 29095159

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189378 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Reticulon-4 receptor Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 36.01 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99PI8 (Residues: 27-337; Coverage: 70%)
Gene names: Ngr1, Nogor, Rtn4r
Sequence domains: Leucine rich repeat
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P41
Unit cell:
a: 90.63Å b: 90.63Å c: 45.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.219 0.248
Expression system: Homo sapiens

Quick links

Citations

1 citations in other articles

The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis.
Aravamudhan et al. (2022)