› 5nxj

X-ray diffraction
2.28Å resolution

SH3 domain from Mouse cortactin (P 1 21 1 crystal form)

Released:
DOI: 10.2210/pdb5nxj/pdb
PDB entry 5nxj coloured by chain, front view.
PDB entry 5nxj coloured by chain, side view.
PDB entry 5nxj coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Twafra S, Dessau M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Src substrate cortactin Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 60 amino acids
Theoretical weight: 6.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60598 (Residues: 490-546; Coverage: 10%)
Gene names: Cttn, Ems1
Sequence domains: Variant SH3 domain

Ligands and Environments

1 bound ligand:
Ligand IPA 2 x IPA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P21
Unit cell:
a: 41.34Å b: 80.08Å c: 61.12Å
α: 90° β: 99.64° γ: 90°
R-values:
R R work R free
0.2 0.198 0.248
Expression system: Escherichia coli BL21(DE3)

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