5n7c

X-ray diffraction
2.45Å resolution

Human TTR altered conformation from soaking in CuCl2.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136168 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 118 amino acids
Theoretical weight: 12.96 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02766 (Residues: 30-147; Coverage: 93%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 2
Spacegroup: P21212
Unit cell:
a: 42.99Å b: 82.54Å c: 67.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.169 0.254