Function and Biology Details
Reaction catalysed:
Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Rhomboid protease GlpG and peptide (preferred)
PDBe Complex ID:
PDB-CPX-140634 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rhomboid protease GlpG
Molecule details ›
Chain: A
Length: 181 amino acids
Theoretical weight: 20.46 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Rhomboid family
Structure domains: Rhomboid-like
Length: 181 amino acids
Theoretical weight: 20.46 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P09391 (Residues: 91-271; Coverage: 66%)
Sequence domains: Rhomboid family
Structure domains: Rhomboid-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I02
Spacegroup:
R32
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
