› 5mdb

Electron Microscopy
8.4Å resolution

The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=-6

Released:
DOI: 10.2210/pdb5mdb/pdb
PDB entry 5mdb coloured by chain, front view.
PDB entry 5mdb coloured by chain, side view.
PDB entry 5mdb coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Primary publication:
The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Mattei S, Glass B, Hagen WJ, Kräusslich HG, Briggs JA
Science 354 1434-1437 (2016)
PMID: 27980210
Related structures: EMD-3480

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetradecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180776 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Gag protein Chains: A, B, C, D, E, F, G, W
Molecule details ›
Chains: A, B, C, D, E, F, G, W
Length: 74 amino acids
Theoretical weight: 8.37 KDa
Source organism: Human immunodeficiency virus 1
UniProt:
  • Canonical: Q72497 (Residues: 280-353; Coverage: 15%)
Gene name: gag
Sequence domains: Gag protein p24 C-terminal domain
Gag protein Chains: H, I, J, a, b, f
Molecule details ›
Chains: H, I, J, a, b, f
Length: 147 amino acids
Theoretical weight: 16.3 KDa
Source organism: Human immunodeficiency virus 1
UniProt:
  • Canonical: Q72497 (Residues: 133-279; Coverage: 29%)
Gene name: gag
Sequence domains: gag protein p24 N-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 8.4Å
Relevant EMDB volumes: EMD-3480

Quick links

Citations

58 review citations

Maturation of retroviruses.
Pornillos et al. (2019)
57 more